Scores
Each row corresponds to a position in the reference protein.  Below each position is the fraction of sequences that contain one of the basic amino acids.  A low fraction indicates the position is either severely gapped or unalignable and has little information.  Expect poor prediction at these positions.
Each column corresponds to one of the twenty amino acids. 
Each entry contains the score at a particular position (row) for an amino acid substitution (column).  Substitutions predicted to be intolerant are highlighted in red.
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 1M 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 2N 1.00 | 0.31 | 0.04 | 0.39 | 0.33 | 0.05 | 0.28 | 0.10 | 0.08 | 0.32 | 0.12 | 0.04 | 0.98 | 0.14 | 0.21 | 0.19 | 1.00 | 0.38 | 0.12 | 0.02 | 0.08 | 
|---|
|
| 3I 1.00 | 0.16 | 0.04 | 0.04 | 0.07 | 0.19 | 0.05 | 0.04 | 1.00 | 0.07 | 0.87 | 0.49 | 0.05 | 0.05 | 0.06 | 0.06 | 0.07 | 0.12 | 0.65 | 0.03 | 0.09 | 
|---|
|
| 4F 1.00 | 0.90 | 0.19 | 0.31 | 0.45 | 0.80 | 0.46 | 0.43 | 0.59 | 0.44 | 1.00 | 0.29 | 0.35 | 0.29 | 0.36 | 0.39 | 0.59 | 0.54 | 0.76 | 0.19 | 0.90 | 
|---|
|
| 5E 1.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 6M 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 7L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 8R 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 9I 1.00 | 0.71 | 0.12 | 0.39 | 0.68 | 0.35 | 0.36 | 0.30 | 0.81 | 1.00 | 0.87 | 0.24 | 0.42 | 0.28 | 0.54 | 0.76 | 0.58 | 0.58 | 0.94 | 0.09 | 0.39 | 
|---|
|
| 10D 1.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 11E 1.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 12G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 13L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 14R 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 15L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 16K 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 17I 1.00 | 0.08 | 0.02 | 0.01 | 0.02 | 0.05 | 0.02 | 0.01 | 0.99 | 0.03 | 0.26 | 0.05 | 0.02 | 0.02 | 0.02 | 0.02 | 0.03 | 0.07 | 1.00 | 0.01 | 0.03 | 
|---|
|
| 18Y 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 
|---|
|
| 19K 1.00 | 0.54 | 0.10 | 0.34 | 0.57 | 0.32 | 0.34 | 0.34 | 0.28 | 1.00 | 0.49 | 0.16 | 0.39 | 0.25 | 0.50 | 0.81 | 0.48 | 0.46 | 0.37 | 0.10 | 0.46 | 
|---|
|
| 20D 1.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 21T 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 22E 1.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 23G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 24Y 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 
|---|
|
| 25Y 1.00 | 0.68 | 0.18 | 0.36 | 0.46 | 0.75 | 0.45 | 0.52 | 0.42 | 0.50 | 0.70 | 0.23 | 0.43 | 0.27 | 0.39 | 0.47 | 0.56 | 0.51 | 0.55 | 0.20 | 1.00 | 
|---|
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 26T 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 27I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 28G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 29I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 30G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 31H 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 32L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 33L 1.00 | 0.09 | 0.02 | 0.02 | 0.04 | 0.13 | 0.03 | 0.02 | 0.89 | 0.04 | 1.00 | 0.14 | 0.03 | 0.03 | 0.04 | 0.04 | 0.04 | 0.07 | 0.50 | 0.02 | 0.05 | 
|---|
|
| 34T 1.00 | 0.64 | 0.11 | 0.29 | 0.44 | 0.25 | 0.25 | 0.18 | 0.49 | 0.47 | 0.68 | 0.43 | 0.31 | 0.23 | 0.32 | 0.33 | 0.63 | 1.00 | 0.69 | 0.06 | 0.26 | 
|---|
|
| 35K 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 36S 1.00 | 0.61 | 0.06 | 0.51 | 0.74 | 0.10 | 0.35 | 0.15 | 0.16 | 0.69 | 0.26 | 0.09 | 0.43 | 0.24 | 0.78 | 0.43 | 1.00 | 0.55 | 0.25 | 0.03 | 0.12 | 
|---|
|
| 37P 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 38S 1.00 | 1.00 | 0.14 | 0.43 | 0.63 | 0.24 | 0.45 | 0.21 | 0.58 | 0.62 | 0.56 | 0.18 | 0.42 | 0.33 | 0.42 | 0.41 | 0.89 | 0.90 | 0.86 | 0.07 | 0.28 | 
|---|
|
| 39L 1.00 | 0.59 | 0.09 | 0.33 | 0.59 | 0.31 | 0.32 | 0.27 | 0.45 | 1.00 | 0.84 | 0.23 | 0.37 | 0.25 | 0.51 | 0.78 | 0.49 | 0.47 | 0.50 | 0.08 | 0.34 | 
|---|
|
| 40N 1.00 | 0.17 | 0.02 | 0.97 | 0.26 | 0.03 | 0.24 | 0.08 | 0.04 | 0.21 | 0.06 | 0.02 | 1.00 | 0.09 | 0.14 | 0.11 | 0.25 | 0.15 | 0.06 | 0.01 | 0.05 | 
|---|
|
| 41A 1.00 | 1.00 | 0.14 | 0.34 | 0.55 | 0.32 | 0.42 | 0.20 | 0.57 | 0.53 | 0.91 | 0.28 | 0.32 | 0.30 | 0.37 | 0.37 | 0.61 | 0.58 | 0.84 | 0.07 | 0.30 | 
|---|
|
| 42A 1.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 43K 1.00 | 0.25 | 0.02 | 0.21 | 0.38 | 0.04 | 0.14 | 0.08 | 0.07 | 1.00 | 0.13 | 0.04 | 0.18 | 0.11 | 0.72 | 0.37 | 0.23 | 0.20 | 0.11 | 0.01 | 0.05 | 
|---|
|
| 44S 1.00 | 0.91 | 0.14 | 0.48 | 0.70 | 0.33 | 0.42 | 0.25 | 0.80 | 0.70 | 0.77 | 0.23 | 0.47 | 0.32 | 0.47 | 0.47 | 0.91 | 0.97 | 1.00 | 0.08 | 0.37 | 
|---|
|
| 45E 1.00 | 0.54 | 0.05 | 0.68 | 1.00 | 0.07 | 0.38 | 0.15 | 0.13 | 0.67 | 0.22 | 0.08 | 0.61 | 0.23 | 0.45 | 0.38 | 0.56 | 0.42 | 0.21 | 0.03 | 0.10 | 
|---|
|
| 46L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 47D 1.00 | 0.43 | 0.05 | 1.00 | 0.59 | 0.06 | 0.35 | 0.12 | 0.10 | 0.45 | 0.16 | 0.06 | 0.49 | 0.18 | 0.31 | 0.25 | 0.96 | 0.41 | 0.16 | 0.02 | 0.08 | 
|---|
|
| 48K 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 49A 1.00 | 0.94 | 0.08 | 0.61 | 1.00 | 0.13 | 0.43 | 0.18 | 0.23 | 0.85 | 0.37 | 0.13 | 0.45 | 0.30 | 0.64 | 0.53 | 0.70 | 0.56 | 0.38 | 0.04 | 0.16 | 
|---|
|
| 50I 1.00 | 0.08 | 0.02 | 0.01 | 0.02 | 0.05 | 0.02 | 0.01 | 0.99 | 0.03 | 0.26 | 0.05 | 0.02 | 0.02 | 0.02 | 0.02 | 0.03 | 0.07 | 1.00 | 0.01 | 0.03 | 
|---|
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 51G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 52R 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 53N 1.00 | 0.54 | 0.05 | 0.69 | 1.00 | 0.07 | 0.39 | 0.15 | 0.14 | 0.67 | 0.22 | 0.08 | 0.62 | 0.23 | 0.45 | 0.38 | 0.57 | 0.42 | 0.21 | 0.03 | 0.10 | 
|---|
|
| 54C 1.00 | 0.42 | 0.26 | 0.09 | 0.15 | 0.23 | 0.12 | 0.12 | 0.92 | 0.16 | 0.64 | 0.16 | 0.12 | 0.12 | 0.13 | 0.13 | 0.20 | 0.33 | 1.00 | 0.05 | 0.22 | 
|---|
|
| 55N 1.00 | 0.50 | 0.07 | 0.48 | 0.51 | 0.10 | 0.33 | 0.14 | 0.16 | 0.51 | 0.22 | 0.08 | 0.70 | 0.21 | 0.33 | 0.32 | 0.78 | 1.00 | 0.24 | 0.03 | 0.13 | 
|---|
|
| 56G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 57V 1.00 | 1.00 | 0.14 | 0.43 | 0.63 | 0.24 | 0.45 | 0.21 | 0.59 | 0.62 | 0.57 | 0.18 | 0.42 | 0.32 | 0.42 | 0.41 | 0.92 | 0.90 | 0.91 | 0.07 | 0.28 | 
|---|
|
| 58I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 59T 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 60K 1.00 | 0.61 | 0.08 | 0.40 | 0.70 | 0.19 | 0.32 | 0.21 | 0.31 | 1.00 | 0.54 | 0.17 | 0.38 | 0.25 | 0.52 | 0.71 | 0.54 | 0.49 | 0.40 | 0.05 | 0.22 | 
|---|
|
| 61D 1.00 | 0.17 | 0.01 | 0.80 | 1.00 | 0.02 | 0.09 | 0.04 | 0.03 | 0.19 | 0.06 | 0.02 | 0.12 | 0.08 | 0.17 | 0.09 | 0.14 | 0.11 | 0.05 | 0.01 | 0.02 | 
|---|
|
| 62E 1.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 63A 1.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 64E 1.00 | 0.61 | 0.06 | 0.58 | 1.00 | 0.08 | 0.31 | 0.13 | 0.18 | 0.69 | 0.26 | 0.09 | 0.39 | 0.24 | 0.47 | 0.40 | 0.61 | 0.59 | 0.28 | 0.03 | 0.09 | 
|---|
|
| 65K 1.00 | 0.59 | 0.06 | 0.44 | 0.70 | 0.09 | 0.31 | 0.15 | 0.19 | 1.00 | 0.28 | 0.10 | 0.40 | 0.24 | 0.47 | 0.58 | 0.64 | 0.75 | 0.29 | 0.03 | 0.11 | 
|---|
|
| 66L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 67F 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 68N 1.00 | 0.54 | 0.05 | 0.69 | 1.00 | 0.07 | 0.39 | 0.15 | 0.14 | 0.67 | 0.22 | 0.08 | 0.62 | 0.23 | 0.45 | 0.38 | 0.57 | 0.42 | 0.21 | 0.03 | 0.10 | 
|---|
|
| 69Q 1.00 | 0.33 | 0.03 | 0.24 | 0.45 | 0.07 | 0.19 | 0.13 | 0.11 | 0.80 | 0.20 | 0.07 | 0.25 | 0.15 | 0.78 | 1.00 | 0.31 | 0.28 | 0.16 | 0.03 | 0.09 | 
|---|
|
| 70D 1.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 71V 1.00 | 0.14 | 0.03 | 0.03 | 0.05 | 0.12 | 0.04 | 0.03 | 0.59 | 0.06 | 0.89 | 0.11 | 0.04 | 0.04 | 0.04 | 0.05 | 0.06 | 0.11 | 1.00 | 0.02 | 0.06 | 
|---|
|
| 72D 1.00 | 0.69 | 0.06 | 0.68 | 1.00 | 0.09 | 0.40 | 0.14 | 0.16 | 0.63 | 0.25 | 0.09 | 0.46 | 0.26 | 0.46 | 0.35 | 0.61 | 0.46 | 0.25 | 0.03 | 0.11 | 
|---|
|
| 73A 1.00 | 0.69 | 0.06 | 0.67 | 1.00 | 0.09 | 0.41 | 0.14 | 0.16 | 0.64 | 0.25 | 0.09 | 0.46 | 0.26 | 0.46 | 0.35 | 0.61 | 0.46 | 0.25 | 0.03 | 0.11 | 
|---|
|
| 74A 1.00 | 1.00 | 0.14 | 0.34 | 0.55 | 0.32 | 0.42 | 0.20 | 0.57 | 0.53 | 0.91 | 0.28 | 0.32 | 0.30 | 0.37 | 0.37 | 0.61 | 0.58 | 0.84 | 0.07 | 0.30 | 
|---|
|
| 75V 1.00 | 1.00 | 0.14 | 0.59 | 0.98 | 0.31 | 0.43 | 0.29 | 0.62 | 0.97 | 0.79 | 0.24 | 0.50 | 0.35 | 0.63 | 0.65 | 0.75 | 0.76 | 0.97 | 0.08 | 0.35 | 
|---|
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 76R 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 77G 1.00 | 0.43 | 0.05 | 1.00 | 0.58 | 0.07 | 0.79 | 0.16 | 0.09 | 0.43 | 0.15 | 0.05 | 0.69 | 0.19 | 0.30 | 0.24 | 0.52 | 0.31 | 0.14 | 0.02 | 0.11 | 
|---|
|
| 78I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 79L 1.00 | 0.61 | 0.08 | 0.39 | 0.69 | 0.22 | 0.32 | 0.22 | 0.38 | 1.00 | 0.67 | 0.19 | 0.38 | 0.25 | 0.52 | 0.73 | 0.52 | 0.48 | 0.46 | 0.06 | 0.23 | 
|---|
|
| 80R 1.00 | 0.74 | 0.08 | 0.54 | 0.81 | 0.14 | 0.43 | 0.20 | 0.21 | 1.00 | 0.35 | 0.12 | 0.51 | 0.29 | 0.56 | 0.84 | 0.92 | 0.66 | 0.32 | 0.05 | 0.18 | 
|---|
|
| 81N 1.00 | 0.31 | 0.06 | 0.50 | 0.36 | 0.17 | 0.38 | 0.65 | 0.13 | 0.39 | 0.22 | 0.07 | 1.00 | 0.15 | 0.25 | 0.27 | 0.41 | 0.28 | 0.17 | 0.05 | 0.26 | 
|---|
|
| 82A 1.00 | 1.00 | 0.04 | 0.14 | 0.20 | 0.04 | 0.21 | 0.04 | 0.06 | 0.19 | 0.10 | 0.04 | 0.13 | 0.12 | 0.12 | 0.12 | 0.90 | 0.23 | 0.12 | 0.01 | 0.04 | 
|---|
|
| 83K 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 84L 1.00 | 0.17 | 0.04 | 0.04 | 0.06 | 0.14 | 0.04 | 0.04 | 0.70 | 0.07 | 0.91 | 0.14 | 0.04 | 0.05 | 0.05 | 0.06 | 0.07 | 0.13 | 1.00 | 0.02 | 0.08 | 
|---|
|
| 85K 1.00 | 0.74 | 0.07 | 0.63 | 0.84 | 0.11 | 0.51 | 0.20 | 0.18 | 1.00 | 0.31 | 0.11 | 0.59 | 0.29 | 0.55 | 0.66 | 0.70 | 0.51 | 0.28 | 0.04 | 0.15 | 
|---|
|
| 86P 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 87V 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 
|---|
|
| 88Y 1.00 | 0.13 | 0.05 | 0.05 | 0.07 | 0.58 | 0.08 | 0.12 | 0.13 | 0.07 | 0.25 | 0.07 | 0.07 | 0.05 | 0.07 | 0.08 | 0.11 | 0.10 | 0.15 | 0.53 | 1.00 | 
|---|
|
| 89D 1.00 | 0.46 | 0.04 | 0.95 | 1.00 | 0.06 | 0.29 | 0.12 | 0.11 | 0.54 | 0.18 | 0.06 | 0.39 | 0.20 | 0.70 | 0.28 | 0.44 | 0.33 | 0.17 | 0.02 | 0.08 | 
|---|
|
| 90S 1.00 | 1.00 | 0.05 | 0.19 | 0.27 | 0.05 | 0.27 | 0.06 | 0.09 | 0.25 | 0.13 | 0.05 | 0.17 | 0.16 | 0.17 | 0.15 | 0.91 | 0.31 | 0.16 | 0.02 | 0.06 | 
|---|
|
| 91L 1.00 | 0.17 | 0.04 | 0.04 | 0.06 | 0.14 | 0.04 | 0.04 | 0.70 | 0.07 | 0.91 | 0.14 | 0.04 | 0.05 | 0.05 | 0.06 | 0.07 | 0.13 | 1.00 | 0.02 | 0.08 | 
|---|
|
| 92D 1.00 | 0.22 | 0.03 | 1.00 | 0.35 | 0.04 | 0.32 | 0.11 | 0.05 | 0.28 | 0.08 | 0.03 | 0.99 | 0.12 | 0.19 | 0.15 | 0.34 | 0.20 | 0.07 | 0.01 | 0.06 | 
|---|
|
| 93A 1.00 | 0.83 | 0.09 | 0.49 | 0.80 | 0.15 | 0.43 | 0.21 | 0.24 | 1.00 | 0.38 | 0.13 | 0.44 | 0.30 | 0.55 | 0.70 | 0.69 | 0.56 | 0.37 | 0.05 | 0.20 | 
|---|
|
| 94V 1.00 | 1.00 | 0.14 | 0.43 | 0.63 | 0.24 | 0.45 | 0.21 | 0.59 | 0.62 | 0.57 | 0.18 | 0.42 | 0.32 | 0.42 | 0.41 | 0.92 | 0.90 | 0.91 | 0.07 | 0.28 | 
|---|
|
| 95R 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 96R 1.00 | 0.26 | 0.03 | 0.18 | 0.35 | 0.05 | 0.15 | 0.10 | 0.08 | 0.63 | 0.16 | 0.05 | 0.19 | 0.12 | 0.80 | 1.00 | 0.24 | 0.22 | 0.12 | 0.02 | 0.07 | 
|---|
|
| 97C 1.00 | 0.66 | 0.23 | 0.19 | 0.28 | 0.42 | 0.27 | 0.25 | 0.63 | 0.30 | 1.00 | 0.35 | 0.23 | 0.21 | 0.24 | 0.26 | 0.40 | 0.46 | 0.82 | 0.10 | 0.44 | 
|---|
|
| 98A 1.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 99L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 100I 1.00 | 0.77 | 0.10 | 0.59 | 1.00 | 0.22 | 0.35 | 0.20 | 0.57 | 0.78 | 0.62 | 0.18 | 0.42 | 0.28 | 0.53 | 0.48 | 0.62 | 0.58 | 0.76 | 0.06 | 0.23 | 
|---|
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 101N 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 102M 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 103V 1.00 | 0.75 | 0.10 | 0.14 | 0.23 | 0.12 | 0.17 | 0.07 | 0.48 | 0.22 | 0.39 | 0.12 | 0.13 | 0.16 | 0.15 | 0.14 | 0.28 | 0.37 | 1.00 | 0.03 | 0.10 | 
|---|
|
| 104F 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 105Q 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 106M 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 107G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 108E 1.00 | 0.77 | 0.09 | 0.58 | 1.00 | 0.17 | 0.33 | 0.18 | 0.45 | 0.73 | 0.47 | 0.15 | 0.39 | 0.27 | 0.50 | 0.43 | 0.58 | 0.56 | 0.68 | 0.04 | 0.18 | 
|---|
|
| 109T 1.00 | 1.00 | 0.12 | 0.64 | 0.75 | 0.17 | 0.63 | 0.22 | 0.23 | 0.74 | 0.36 | 0.13 | 0.63 | 0.35 | 0.48 | 0.47 | 1.00 | 0.82 | 0.36 | 0.06 | 0.23 | 
|---|
|
| 110G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 111V 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 
|---|
|
| 112A 1.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 113G 1.00 | 0.60 | 0.06 | 0.51 | 0.67 | 0.09 | 0.62 | 0.16 | 0.15 | 1.00 | 0.25 | 0.09 | 0.48 | 0.24 | 0.44 | 0.53 | 0.56 | 0.41 | 0.22 | 0.03 | 0.12 | 
|---|
|
| 114F 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 115T 1.00 | 0.37 | 0.05 | 0.35 | 0.37 | 0.07 | 0.24 | 0.11 | 0.12 | 0.37 | 0.16 | 0.06 | 0.75 | 0.16 | 0.24 | 0.23 | 0.57 | 1.00 | 0.18 | 0.02 | 0.09 | 
|---|
|
| 116N 1.00 | 0.50 | 0.07 | 0.48 | 0.51 | 0.10 | 0.33 | 0.14 | 0.16 | 0.51 | 0.22 | 0.08 | 0.70 | 0.21 | 0.33 | 0.32 | 0.78 | 1.00 | 0.24 | 0.03 | 0.13 | 
|---|
|
| 117S 1.00 | 1.00 | 0.14 | 0.52 | 0.75 | 0.32 | 0.51 | 0.27 | 0.42 | 0.76 | 0.69 | 0.22 | 0.50 | 0.35 | 0.51 | 0.51 | 0.99 | 0.93 | 0.58 | 0.09 | 0.38 | 
|---|
|
| 118L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 119R 1.00 | 0.63 | 0.07 | 0.43 | 0.70 | 0.14 | 0.34 | 0.20 | 0.22 | 1.00 | 0.35 | 0.12 | 0.43 | 0.26 | 0.52 | 0.81 | 0.69 | 0.76 | 0.33 | 0.05 | 0.18 | 
|---|
|
| 120M 1.00 | 1.00 | 0.13 | 0.32 | 0.50 | 0.30 | 0.39 | 0.19 | 0.54 | 0.49 | 0.86 | 0.34 | 0.29 | 0.28 | 0.34 | 0.34 | 0.57 | 0.54 | 0.78 | 0.07 | 0.28 | 
|---|
|
| 121L 1.00 | 0.07 | 0.02 | 0.02 | 0.03 | 0.12 | 0.02 | 0.02 | 0.24 | 0.04 | 1.00 | 0.52 | 0.02 | 0.03 | 0.04 | 0.03 | 0.03 | 0.05 | 0.17 | 0.02 | 0.04 | 
|---|
|
| 122Q 1.00 | 0.62 | 0.09 | 0.40 | 0.68 | 0.32 | 0.31 | 0.23 | 0.47 | 0.76 | 1.00 | 0.26 | 0.36 | 0.24 | 0.46 | 0.54 | 0.51 | 0.47 | 0.50 | 0.07 | 0.29 | 
|---|
|
| 123Q 1.00 | 0.85 | 0.08 | 0.61 | 1.00 | 0.13 | 0.43 | 0.18 | 0.23 | 0.85 | 0.36 | 0.13 | 0.45 | 0.30 | 0.57 | 0.53 | 0.70 | 0.56 | 0.37 | 0.04 | 0.16 | 
|---|
|
| 124K 1.00 | 0.74 | 0.07 | 0.63 | 0.84 | 0.11 | 0.51 | 0.20 | 0.18 | 1.00 | 0.31 | 0.11 | 0.59 | 0.29 | 0.55 | 0.66 | 0.70 | 0.51 | 0.28 | 0.04 | 0.15 | 
|---|
|
| 125R 1.00 | 0.67 | 0.06 | 0.75 | 1.00 | 0.10 | 0.44 | 0.18 | 0.18 | 0.85 | 0.30 | 0.10 | 0.59 | 0.27 | 0.55 | 0.53 | 0.69 | 0.52 | 0.27 | 0.03 | 0.13 | 
|---|
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 126W 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 
|---|
|
| 127D 1.00 | 0.17 | 0.01 | 0.80 | 1.00 | 0.02 | 0.09 | 0.04 | 0.03 | 0.19 | 0.06 | 0.02 | 0.12 | 0.08 | 0.17 | 0.09 | 0.14 | 0.11 | 0.05 | 0.01 | 0.02 | 
|---|
|
| 128E 1.00 | 0.34 | 0.02 | 0.36 | 1.00 | 0.04 | 0.18 | 0.08 | 0.09 | 0.85 | 0.14 | 0.05 | 0.23 | 0.14 | 0.31 | 0.31 | 0.30 | 0.25 | 0.13 | 0.01 | 0.04 | 
|---|
|
| 129A 1.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 130A 1.00 | 0.75 | 0.19 | 0.32 | 0.43 | 0.76 | 0.45 | 0.51 | 0.44 | 0.44 | 0.71 | 0.23 | 0.39 | 0.27 | 0.37 | 0.43 | 0.57 | 0.51 | 0.59 | 0.20 | 1.00 | 
|---|
|
| 131V 1.00 | 0.83 | 0.11 | 0.47 | 0.81 | 0.20 | 0.36 | 0.22 | 0.61 | 1.00 | 0.60 | 0.18 | 0.43 | 0.30 | 0.56 | 0.68 | 0.64 | 0.64 | 0.87 | 0.06 | 0.23 | 
|---|
|
| 132N 1.00 | 1.00 | 0.11 | 0.81 | 0.99 | 0.18 | 0.63 | 0.25 | 0.26 | 0.92 | 0.41 | 0.14 | 0.78 | 0.36 | 0.59 | 0.56 | 0.96 | 0.76 | 0.42 | 0.05 | 0.23 | 
|---|
|
| 133L 1.00 | 1.00 | 0.15 | 0.50 | 0.71 | 0.44 | 0.58 | 0.34 | 0.59 | 0.74 | 0.94 | 0.27 | 0.49 | 0.35 | 0.50 | 0.54 | 0.77 | 0.58 | 0.66 | 0.11 | 0.50 | 
|---|
|
| 134A 1.00 | 0.83 | 0.09 | 0.49 | 0.80 | 0.15 | 0.43 | 0.21 | 0.24 | 1.00 | 0.38 | 0.13 | 0.44 | 0.30 | 0.55 | 0.70 | 0.69 | 0.56 | 0.37 | 0.05 | 0.20 | 
|---|
|
| 135K 1.00 | 0.56 | 0.05 | 0.77 | 1.00 | 0.06 | 0.37 | 0.14 | 0.14 | 0.78 | 0.22 | 0.08 | 0.50 | 0.24 | 0.48 | 0.39 | 0.57 | 0.43 | 0.21 | 0.02 | 0.08 | 
|---|
|
| 136S 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 137R 1.00 | 0.58 | 0.09 | 0.33 | 0.59 | 0.30 | 0.31 | 0.27 | 0.44 | 1.00 | 0.81 | 0.22 | 0.37 | 0.25 | 0.51 | 0.77 | 0.49 | 0.46 | 0.49 | 0.08 | 0.33 | 
|---|
|
| 138W 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 
|---|
|
| 139Y 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 
|---|
|
| 140N 1.00 | 0.58 | 0.06 | 0.66 | 0.81 | 0.11 | 0.43 | 0.19 | 0.16 | 0.80 | 0.28 | 0.10 | 1.00 | 0.25 | 0.87 | 0.50 | 0.63 | 0.49 | 0.24 | 0.04 | 0.15 | 
|---|
|
| 141Q 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 142T 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 143P 1.00 | 0.39 | 0.04 | 0.30 | 0.50 | 0.06 | 0.22 | 0.11 | 0.11 | 1.00 | 0.18 | 0.06 | 0.26 | 0.56 | 0.33 | 0.42 | 0.35 | 0.30 | 0.17 | 0.02 | 0.08 | 
|---|
|
| 144N 1.00 | 0.48 | 0.07 | 0.87 | 0.53 | 0.10 | 0.70 | 0.22 | 0.11 | 0.52 | 0.18 | 0.06 | 1.00 | 0.23 | 0.34 | 0.31 | 0.66 | 0.38 | 0.16 | 0.04 | 0.16 | 
|---|
|
| 145R 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 146A 1.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 147K 1.00 | 0.60 | 0.06 | 0.48 | 0.71 | 0.08 | 0.35 | 0.14 | 0.16 | 1.00 | 0.26 | 0.09 | 0.43 | 0.23 | 0.45 | 0.50 | 0.84 | 0.53 | 0.24 | 0.03 | 0.10 | 
|---|
|
| 148R 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 149V 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 
|---|
|
| 150I 1.00 | 0.48 | 0.09 | 0.16 | 0.25 | 0.17 | 0.13 | 0.10 | 0.93 | 0.27 | 0.56 | 0.15 | 0.18 | 0.15 | 0.18 | 0.18 | 0.37 | 0.72 | 1.00 | 0.04 | 0.15 | 
|---|
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 151T 1.00 | 0.64 | 0.11 | 0.29 | 0.44 | 0.25 | 0.25 | 0.18 | 0.49 | 0.47 | 0.68 | 0.43 | 0.31 | 0.23 | 0.32 | 0.33 | 0.63 | 1.00 | 0.69 | 0.06 | 0.26 | 
|---|
|
| 152T 1.00 | 0.49 | 0.09 | 0.17 | 0.26 | 0.17 | 0.14 | 0.10 | 0.78 | 0.27 | 0.56 | 0.15 | 0.18 | 0.15 | 0.18 | 0.19 | 0.38 | 0.59 | 1.00 | 0.04 | 0.15 | 
|---|
|
| 153F 1.00 | 0.22 | 0.06 | 0.07 | 0.10 | 0.59 | 0.10 | 0.12 | 1.00 | 0.11 | 1.00 | 0.23 | 0.09 | 0.08 | 0.10 | 0.11 | 0.13 | 0.17 | 0.78 | 0.08 | 0.35 | 
|---|
|
| 154R 1.00 | 0.58 | 0.09 | 0.33 | 0.59 | 0.30 | 0.31 | 0.27 | 0.44 | 1.00 | 0.81 | 0.22 | 0.37 | 0.25 | 0.51 | 0.77 | 0.49 | 0.46 | 0.49 | 0.08 | 0.33 | 
|---|
|
| 155T 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 156G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 157T 1.00 | 0.37 | 0.05 | 0.35 | 0.37 | 0.07 | 0.24 | 0.11 | 0.12 | 0.37 | 0.16 | 0.06 | 0.75 | 0.16 | 0.24 | 0.23 | 0.57 | 1.00 | 0.18 | 0.02 | 0.09 | 
|---|
|
| 158W 1.00 | 0.20 | 0.06 | 0.07 | 0.10 | 0.44 | 0.10 | 0.14 | 0.36 | 0.12 | 1.00 | 0.19 | 0.10 | 0.08 | 0.11 | 0.12 | 0.14 | 0.15 | 0.31 | 0.31 | 0.40 | 
|---|
|
| 159D 1.00 | 0.17 | 0.01 | 0.80 | 1.00 | 0.02 | 0.09 | 0.04 | 0.03 | 0.19 | 0.06 | 0.02 | 0.12 | 0.08 | 0.17 | 0.09 | 0.14 | 0.11 | 0.05 | 0.01 | 0.02 | 
|---|
|
| 160A 1.00 | 1.00 | 0.04 | 0.14 | 0.20 | 0.04 | 0.21 | 0.04 | 0.06 | 0.19 | 0.10 | 0.04 | 0.13 | 0.12 | 0.12 | 0.12 | 0.90 | 0.23 | 0.12 | 0.01 | 0.04 | 
|---|
|
| 161Y 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 
|---|
|
| 162K 0.50 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 163N 0.50 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 164L 0.50 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|