Scores
Each row corresponds to a position in the reference protein.  Below each position is the fraction of sequences that contain one of the basic amino acids.  A low fraction indicates the position is either severely gapped or unalignable and has little information.  Expect poor prediction at these positions.
Each column corresponds to one of the twenty amino acids. 
Each entry contains the score at a particular position (row) for an amino acid substitution (column).  Substitutions predicted to be intolerant are highlighted in red.
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 1P 0.85 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 2Q 0.95 | 0.01 | 0.00 | 0.02 | 0.41 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.01 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 3I 0.95 | 0.03 | 0.01 | 0.01 | 0.01 | 0.77 | 0.01 | 0.01 | 1.00 | 0.01 | 0.71 | 0.08 | 0.01 | 0.01 | 0.01 | 0.01 | 0.02 | 0.03 | 0.32 | 0.03 | 0.25 | 
|---|
|
| 4T 0.95 | 0.09 | 0.02 | 0.04 | 0.02 | 0.01 | 0.03 | 0.01 | 0.02 | 0.03 | 0.02 | 0.01 | 0.06 | 0.35 | 0.03 | 0.02 | 0.97 | 1.00 | 0.04 | 0.01 | 0.01 | 
|---|
|
| 5L 0.95 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 6W 0.95 | 0.03 | 0.00 | 0.01 | 0.01 | 0.03 | 0.03 | 0.00 | 0.01 | 0.01 | 0.01 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.12 | 0.02 | 0.01 | 1.00 | 0.02 | 
|---|
|
| 7Q 0.95 | 0.02 | 0.00 | 0.00 | 0.02 | 0.00 | 0.01 | 0.02 | 0.01 | 0.60 | 0.02 | 0.01 | 0.02 | 0.01 | 0.91 | 1.00 | 0.01 | 0.02 | 0.01 | 0.00 | 0.01 | 
|---|
|
| 8R 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 9P 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 10L 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.03 | 0.01 | 0.00 | 0.80 | 0.01 | 1.00 | 0.15 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.01 | 0.87 | 0.00 | 0.01 | 
|---|
|
| 11V 1.00 | 0.12 | 0.02 | 0.02 | 0.17 | 0.02 | 0.04 | 0.04 | 0.17 | 0.47 | 0.11 | 0.03 | 0.05 | 0.05 | 0.12 | 0.32 | 0.05 | 0.10 | 1.00 | 0.01 | 0.03 | 
|---|
|
| 12T 1.00 | 0.17 | 0.01 | 0.10 | 0.32 | 0.02 | 0.08 | 0.07 | 0.05 | 0.54 | 0.09 | 0.03 | 0.11 | 0.13 | 0.21 | 0.59 | 0.15 | 1.00 | 0.07 | 0.01 | 0.03 | 
|---|
|
| 13I 1.00 | 0.67 | 0.10 | 0.01 | 0.02 | 0.01 | 0.00 | 0.00 | 0.62 | 0.02 | 0.09 | 0.03 | 0.01 | 0.02 | 0.01 | 0.01 | 0.02 | 0.08 | 1.00 | 0.00 | 0.00 | 
|---|
|
| 14K 1.00 | 0.50 | 0.18 | 0.20 | 0.27 | 0.70 | 0.33 | 0.54 | 0.40 | 0.30 | 0.64 | 0.22 | 0.31 | 0.20 | 0.29 | 0.35 | 0.40 | 0.39 | 0.50 | 0.18 | 1.00 | 
|---|
|
| 15I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.16 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.27 | 0.00 | 0.00 | 
|---|
|
| 16G 1.00 | 0.22 | 0.01 | 0.65 | 1.00 | 0.02 | 0.25 | 0.08 | 0.02 | 0.22 | 0.05 | 0.02 | 0.30 | 0.13 | 0.25 | 0.07 | 0.20 | 0.12 | 0.05 | 0.01 | 0.04 | 
|---|
|
| 17G 1.00 | 0.04 | 0.00 | 0.12 | 0.09 | 0.00 | 1.00 | 0.01 | 0.00 | 0.02 | 0.01 | 0.00 | 0.04 | 0.01 | 0.01 | 0.01 | 0.16 | 0.01 | 0.04 | 0.00 | 0.00 | 
|---|
|
| 18Q 1.00 | 0.33 | 0.06 | 0.09 | 0.17 | 0.06 | 0.08 | 0.21 | 0.24 | 0.35 | 0.22 | 0.07 | 0.13 | 0.12 | 1.00 | 0.28 | 0.28 | 0.57 | 0.67 | 0.02 | 0.07 | 
|---|
|
| 19L 1.00 | 1.00 | 0.12 | 0.13 | 0.13 | 0.06 | 0.45 | 0.04 | 0.16 | 0.16 | 0.24 | 0.08 | 0.19 | 0.36 | 0.12 | 0.11 | 0.96 | 0.97 | 0.35 | 0.02 | 0.05 | 
|---|
|
| 20K 1.00 | 0.18 | 0.06 | 0.01 | 0.03 | 0.04 | 0.01 | 0.01 | 0.60 | 0.22 | 0.23 | 0.06 | 0.02 | 0.04 | 0.02 | 0.02 | 0.03 | 0.14 | 1.00 | 0.01 | 0.02 | 
|---|
|
| 21E 1.00 | 0.01 | 0.00 | 0.01 | 1.00 | 0.00 | 0.01 | 0.01 | 0.00 | 0.33 | 0.01 | 0.00 | 0.01 | 0.01 | 0.11 | 0.22 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 
|---|
|
| 22A 1.00 | 1.00 | 0.01 | 0.00 | 0.01 | 0.00 | 0.02 | 0.00 | 0.03 | 0.01 | 0.02 | 0.01 | 0.00 | 0.01 | 0.01 | 0.00 | 0.02 | 0.02 | 0.48 | 0.00 | 0.00 | 
|---|
|
| 23L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 24L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 25D 1.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 26T 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.13 | 1.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 27G 1.00 | 0.01 | 0.00 | 0.01 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.01 | 0.01 | 0.00 | 0.04 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 28A 1.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.04 | 0.00 | 0.00 | 
|---|
|
| 29D 1.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.04 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 30D 1.00 | 0.02 | 0.01 | 1.00 | 0.04 | 0.01 | 0.03 | 0.01 | 0.13 | 0.02 | 0.02 | 0.01 | 0.03 | 0.02 | 0.01 | 0.01 | 0.02 | 0.02 | 0.02 | 0.00 | 0.01 | 
|---|
|
| 31T 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.46 | 1.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 32V 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.55 | 0.00 | 0.00 | 
|---|
|
| 33L 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.21 | 0.00 | 0.00 | 1.00 | 0.00 | 0.91 | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.98 | 0.00 | 0.01 | 
|---|
|
| 34E 1.00 | 0.77 | 0.04 | 0.44 | 1.00 | 0.04 | 0.29 | 0.09 | 0.13 | 0.76 | 0.21 | 0.07 | 0.41 | 0.19 | 0.46 | 0.37 | 0.61 | 0.44 | 0.20 | 0.01 | 0.03 | 
|---|
|
| 35E 1.00 | 0.17 | 0.01 | 0.54 | 1.00 | 0.02 | 0.29 | 0.06 | 0.02 | 0.18 | 0.04 | 0.01 | 0.23 | 0.10 | 0.20 | 0.08 | 0.15 | 0.09 | 0.04 | 0.01 | 0.03 | 
|---|
|
| 36M 1.00 | 0.75 | 0.09 | 0.38 | 0.78 | 0.10 | 0.24 | 0.12 | 1.00 | 0.67 | 0.38 | 0.48 | 0.37 | 0.22 | 0.39 | 0.35 | 0.49 | 0.59 | 0.73 | 0.03 | 0.10 | 
|---|
|
| 37S 1.00 | 0.07 | 0.00 | 0.96 | 1.00 | 0.01 | 0.05 | 0.02 | 0.01 | 0.30 | 0.02 | 0.01 | 0.63 | 0.03 | 0.25 | 0.04 | 0.35 | 0.05 | 0.02 | 0.00 | 0.01 | 
|---|
|
| 38L 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.02 | 0.00 | 0.00 | 0.02 | 0.00 | 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.11 | 0.01 | 
|---|
|
| 39P 1.00 | 0.77 | 0.08 | 0.42 | 0.33 | 0.05 | 1.00 | 0.13 | 0.07 | 0.67 | 0.14 | 0.06 | 0.47 | 0.88 | 0.37 | 0.42 | 0.66 | 0.29 | 0.15 | 0.02 | 0.08 | 
|---|
|
| 40G 1.00 | 0.11 | 0.02 | 0.39 | 0.13 | 0.02 | 1.00 | 0.06 | 0.02 | 0.13 | 0.03 | 0.01 | 0.37 | 0.28 | 0.08 | 0.10 | 0.45 | 0.33 | 0.03 | 0.01 | 0.03 | 
|---|
|
| 41R 1.00 | 0.65 | 0.05 | 0.71 | 0.86 | 0.05 | 0.33 | 0.26 | 0.16 | 1.00 | 0.33 | 0.09 | 0.97 | 0.29 | 0.51 | 0.75 | 0.70 | 0.56 | 0.25 | 0.02 | 0.05 | 
|---|
|
| 42W 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.05 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.48 | 
|---|
|
| 43K 0.95 | 0.28 | 0.05 | 0.20 | 0.30 | 0.13 | 0.16 | 0.13 | 0.12 | 1.00 | 0.19 | 0.07 | 0.18 | 0.11 | 0.34 | 0.43 | 0.49 | 0.50 | 0.21 | 0.04 | 0.18 | 
|---|
|
| 44P 1.00 | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.07 | 0.01 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 45K 1.00 | 0.03 | 0.00 | 0.01 | 0.02 | 0.00 | 0.01 | 0.01 | 0.01 | 1.00 | 0.02 | 0.01 | 0.01 | 0.01 | 0.02 | 0.05 | 0.01 | 0.02 | 0.14 | 0.00 | 0.00 | 
|---|
|
| 46M 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 1.00 | 0.00 | 0.08 | 0.75 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.22 | 0.00 | 0.00 | 
|---|
|
| 47I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.69 | 0.00 | 0.00 | 
|---|
|
| 48G 1.00 | 0.01 | 0.00 | 0.02 | 0.01 | 0.00 | 1.00 | 0.12 | 0.00 | 0.01 | 0.00 | 0.00 | 0.03 | 0.01 | 0.01 | 0.01 | 0.02 | 0.01 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 49G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 50I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 51G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 52G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 53F 1.00 | 0.37 | 0.06 | 0.84 | 0.26 | 0.28 | 0.79 | 0.19 | 0.04 | 0.26 | 0.08 | 0.03 | 1.00 | 0.19 | 0.17 | 0.14 | 0.55 | 0.22 | 0.07 | 0.02 | 0.11 | 
|---|
|
| 54I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 1.00 | 0.00 | 0.27 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.02 | 0.00 | 0.00 | 
|---|
|
| 55K 1.00 | 0.12 | 0.01 | 0.06 | 0.16 | 0.02 | 0.10 | 0.14 | 0.05 | 1.00 | 0.11 | 0.04 | 0.44 | 0.16 | 0.26 | 0.69 | 0.11 | 0.12 | 0.06 | 0.02 | 0.05 | 
|---|
|
| 56V 1.00 | 0.06 | 0.01 | 0.00 | 0.01 | 0.01 | 0.00 | 0.00 | 0.07 | 0.01 | 0.05 | 0.17 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.50 | 1.00 | 0.00 | 0.00 | 
|---|
|
| 57R 1.00 | 0.01 | 0.00 | 0.00 | 0.01 | 0.00 | 0.04 | 0.01 | 0.00 | 1.00 | 0.01 | 0.00 | 0.01 | 0.01 | 0.02 | 0.68 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 58Q 1.00 | 0.02 | 0.00 | 0.04 | 1.00 | 0.00 | 0.01 | 0.01 | 0.00 | 0.23 | 0.01 | 0.00 | 0.01 | 0.01 | 0.84 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 59Y 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.13 | 0.00 | 0.00 | 0.04 | 0.00 | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.12 | 0.00 | 0.01 | 0.02 | 1.00 | 
|---|
|
| 60D 1.00 | 0.15 | 0.01 | 1.00 | 0.22 | 0.02 | 0.15 | 0.06 | 0.04 | 0.78 | 0.06 | 0.02 | 0.28 | 0.07 | 0.24 | 0.35 | 0.25 | 0.13 | 0.05 | 0.01 | 0.03 | 
|---|
|
| 61Q 1.00 | 0.04 | 0.01 | 0.77 | 0.06 | 0.01 | 0.25 | 0.04 | 0.00 | 0.05 | 0.01 | 0.00 | 1.00 | 0.03 | 0.70 | 0.03 | 0.10 | 0.04 | 0.01 | 0.00 | 0.02 | 
|---|
|
| 62I 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.92 | 0.00 | 0.07 | 0.01 | 0.00 | 0.00 | 0.00 | 0.12 | 0.00 | 0.01 | 1.00 | 0.00 | 0.01 | 
|---|
|
| 63L 1.00 | 0.72 | 0.17 | 0.46 | 1.00 | 0.63 | 0.43 | 0.56 | 0.41 | 0.87 | 0.78 | 0.24 | 0.45 | 0.34 | 0.59 | 0.71 | 0.59 | 0.56 | 0.54 | 0.17 | 0.92 | 
|---|
|
| 64I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.10 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.51 | 0.00 | 0.00 | 
|---|
|
| 65E 1.00 | 0.10 | 0.01 | 0.18 | 1.00 | 0.01 | 0.22 | 0.02 | 0.02 | 0.37 | 0.04 | 0.01 | 0.07 | 0.05 | 0.24 | 0.19 | 0.08 | 0.07 | 0.03 | 0.00 | 0.01 | 
|---|
|
| 66I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 1.00 | 0.00 | 0.30 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.91 | 0.00 | 0.00 | 
|---|
|
| 67C 1.00 | 0.39 | 0.09 | 0.04 | 0.09 | 0.15 | 0.03 | 0.05 | 0.67 | 0.09 | 0.70 | 0.17 | 0.05 | 0.09 | 0.07 | 0.07 | 0.09 | 0.28 | 1.00 | 0.03 | 0.08 | 
|---|
|
| 68G 1.00 | 0.02 | 0.00 | 0.35 | 0.02 | 0.00 | 1.00 | 0.02 | 0.00 | 0.02 | 0.00 | 0.00 | 0.50 | 0.01 | 0.02 | 0.01 | 0.04 | 0.02 | 0.00 | 0.00 | 0.01 | 
|---|
|
| 69H 1.00 | 0.03 | 0.00 | 0.01 | 0.05 | 0.01 | 0.02 | 0.34 | 0.01 | 1.00 | 0.03 | 0.01 | 0.03 | 0.03 | 0.10 | 0.39 | 0.03 | 0.04 | 0.02 | 0.01 | 0.04 | 
|---|
|
| 70K 1.00 | 0.17 | 0.02 | 0.05 | 0.22 | 0.06 | 0.13 | 0.13 | 0.19 | 1.00 | 0.20 | 0.08 | 0.15 | 0.12 | 0.33 | 0.81 | 0.14 | 0.17 | 0.18 | 0.03 | 0.09 | 
|---|
|
| 71A 1.00 | 0.65 | 0.03 | 0.01 | 0.02 | 0.02 | 0.00 | 0.00 | 0.44 | 0.02 | 0.32 | 0.03 | 0.01 | 0.03 | 0.01 | 0.01 | 0.02 | 0.26 | 1.00 | 0.00 | 0.01 | 
|---|
|
| 72I 1.00 | 0.39 | 0.10 | 0.09 | 0.17 | 0.29 | 0.14 | 0.20 | 0.79 | 0.35 | 0.61 | 0.16 | 0.15 | 0.13 | 0.19 | 0.33 | 0.19 | 0.31 | 1.00 | 0.07 | 0.34 | 
|---|
|
| 73G 1.00 | 0.33 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.03 | 0.02 | 0.01 | 0.01 | 0.00 | 0.00 | 
|---|
|
| 74T 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.20 | 1.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 75V 0.95 | 0.05 | 0.03 | 0.03 | 0.03 | 0.07 | 0.04 | 0.06 | 1.00 | 0.03 | 0.06 | 0.03 | 0.04 | 0.03 | 0.04 | 0.04 | 0.04 | 0.04 | 1.00 | 0.03 | 0.09 | 
|---|
| pos | A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | 
|---|
| 76L 0.95 | 0.04 | 0.02 | 0.02 | 0.02 | 0.05 | 0.03 | 0.04 | 0.03 | 0.02 | 1.00 | 0.52 | 0.03 | 0.02 | 0.02 | 0.03 | 0.03 | 0.03 | 0.04 | 0.02 | 0.06 | 
|---|
|
| 77V 0.95 | 0.15 | 0.06 | 0.07 | 0.09 | 0.20 | 0.10 | 0.16 | 0.63 | 0.09 | 0.27 | 0.07 | 0.10 | 0.07 | 0.09 | 0.11 | 0.12 | 0.87 | 1.00 | 0.06 | 0.28 | 
|---|
|
| 78G 0.95 | 0.02 | 0.01 | 0.01 | 0.01 | 0.02 | 1.00 | 0.02 | 0.02 | 0.01 | 0.02 | 0.01 | 0.01 | 0.01 | 0.01 | 0.02 | 0.02 | 0.02 | 0.02 | 0.01 | 0.03 | 
|---|
|
| 79P 0.95 | 0.47 | 0.10 | 0.80 | 0.23 | 0.34 | 0.20 | 0.27 | 0.21 | 0.23 | 0.34 | 0.12 | 0.20 | 1.00 | 0.20 | 0.22 | 0.46 | 0.25 | 0.27 | 0.10 | 0.47 | 
|---|
|
| 80T 0.95 | 0.02 | 0.01 | 0.01 | 0.01 | 0.02 | 0.01 | 0.02 | 0.02 | 0.01 | 0.02 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.02 | 1.00 | 0.02 | 0.01 | 0.03 | 
|---|
|
| 81P 0.95 | 0.02 | 0.01 | 0.01 | 0.01 | 0.02 | 0.01 | 0.02 | 0.02 | 0.01 | 0.02 | 0.01 | 0.01 | 1.00 | 0.01 | 0.02 | 0.02 | 0.02 | 0.02 | 0.01 | 0.03 | 
|---|
|
| 82V 0.95 | 0.04 | 0.02 | 0.02 | 0.03 | 0.05 | 0.03 | 0.04 | 1.00 | 0.03 | 0.05 | 0.02 | 0.03 | 0.02 | 0.03 | 0.03 | 0.03 | 0.03 | 0.65 | 0.02 | 0.07 | 
|---|
|
| 83N 0.95 | 0.02 | 0.01 | 0.10 | 0.02 | 0.03 | 0.02 | 0.02 | 0.02 | 0.02 | 0.03 | 0.01 | 1.00 | 0.01 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.01 | 0.04 | 
|---|
|
| 84I 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 85I 1.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.52 | 0.00 | 0.00 | 1.00 | 0.00 | 0.34 | 0.04 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.01 | 0.05 | 0.01 | 0.01 | 
|---|
|
| 86G 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 87R 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 88N 1.00 | 0.00 | 0.00 | 0.13 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 89L 1.00 | 0.02 | 0.20 | 0.00 | 0.01 | 0.12 | 0.00 | 0.00 | 0.90 | 0.01 | 1.00 | 0.12 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.16 | 0.01 | 0.01 | 
|---|
|
| 90L 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.01 | 0.00 | 1.00 | 0.08 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 
|---|
|
| 91T 0.97 | 0.29 | 0.01 | 0.07 | 0.23 | 0.00 | 0.03 | 0.01 | 0.01 | 0.05 | 0.02 | 0.01 | 0.09 | 0.02 | 0.20 | 0.03 | 0.07 | 1.00 | 0.02 | 0.00 | 0.01 | 
|---|
|
| 92Q 0.97 | 1.00 | 0.08 | 0.36 | 0.58 | 0.05 | 0.52 | 0.10 | 0.12 | 0.73 | 0.21 | 0.08 | 0.31 | 0.29 | 0.62 | 0.46 | 0.62 | 0.44 | 0.22 | 0.02 | 0.05 | 
|---|
|
| 93I 0.97 | 0.22 | 0.00 | 0.00 | 0.00 | 0.04 | 0.00 | 0.00 | 0.49 | 0.01 | 1.00 | 0.12 | 0.00 | 0.01 | 0.01 | 0.01 | 0.00 | 0.01 | 0.05 | 0.00 | 0.01 | 
|---|
|
| 94G 0.97 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 95C 0.97 | 1.00 | 0.15 | 0.07 | 0.09 | 0.11 | 0.53 | 0.03 | 0.16 | 0.10 | 0.46 | 0.17 | 0.07 | 0.24 | 0.08 | 0.08 | 0.48 | 0.18 | 0.22 | 0.02 | 0.06 | 
|---|
|
| 96T 0.97 | 0.12 | 0.02 | 0.05 | 0.08 | 0.02 | 0.06 | 0.05 | 0.04 | 0.65 | 0.06 | 0.03 | 0.10 | 0.07 | 0.12 | 0.43 | 0.73 | 1.00 | 0.06 | 0.01 | 0.03 | 
|---|
|
| 97L 0.97 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|
|
| 98N 0.82 | 0.03 | 0.00 | 0.03 | 0.01 | 0.00 | 0.03 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | 1.00 | 0.01 | 0.01 | 0.01 | 0.03 | 0.02 | 0.08 | 0.00 | 0.00 | 
|---|
|
| 99F 0.50 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 
|---|